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From: | Eric Hack |
Subject: | Multiple experiments with a single individual |
Date: | Thu, 8 Jan 2004 12:08:02 -0600 |
Frederic,
I have a question about how to define the levels in the simulation input file to implement a hierarchical population model. I have data on several individuals, and multiple experiments were performed per individual. Suppose I have Experiments A through Z. Then my file might look like the following.
Level { Distributions for population means Distributions for population variances Likelihood definition Level { Distributions at the subject level Experiment { A Individual 1 experiment } Experiment { B Individual 2 experiment } … Experiment { Z Individual N experiment } } }
MCSim “clones” the subject level distributions, and each experiment would receive a different parameter vector. Suppose experiments B and C were performed on the same individual. How do I tell MCSim to use the same parameters for experiments B and C? Should I enclose them in a third level statement, such as the following?
Level { Distributions for population means Distributions for population variances Likelihood definition Level { Distributions at the subject level Experiment { A Individual 1 experiment } Level { #Open level for individual in experiments B and C Experiment { B Individual 2 experiment number 1 } Experiment { C Individual 2 experiment number 2 } } #Close level for individual in experiments B and C … Experiment { Z Individual N experiment } } }
Thank you, Eric Hack
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